Hi
Muse does not create responsive sites. However Muse gives the flexibility to create different versions for tablets and mobiles.
Muse also provides a few features for creating a web page design that corresponds to some degree of 'responsiveness':
1) Browser Fill Images set to Scale to Fill or Scale to Fit (generally with the page fill and stroke set to none, so the browser fill is the background everywhere)
2) 100% Browser width objects (which can contain background images set to Scale to Fill, Scale to Fit, Center, etc. and which can include text frames)
3) Pinned items, which maintain a specific location offset from one or two edges of the browser window
4) Full screen slideshows
5) 100% width slideshow hero images
6) 100% width Adobe Edge Animate animations (.oam files)
7) Some third-party widgets <https://creative.adobe.com/addons?pp=MUSE>
But even if these features dont fulfill your need, You can always use Adobe EDGE REFLOW to create a Responsive website. Please go through this video for a better understanding how to to do it :
https://www.youtube.com/watch?v=hde9qB6vMf4
Cheers,
Rohit Nair